Carbapenemase-producing Enterobacteriaceae

Carbapenemase-producing Enterobacteriaceae

At BioDecon, we have helped many hospitals deal with Carbapenemase-producing Enterobacteriaceae (CPE) outbreaks.

This case study takes a look at a project where we were called in by a hospital to provide CPE cleaning services. We swung into action, and in just an hour, we were able to clean an ICU ward. For privacy reasons, we are not able to identify the hospital.

What Is CPE?

Carbapenemase-producing Enterobacteriaceae (CPE), also referred to as Carbapenem-resistant Enterobacteriaceae (CRE) are a class of gram-negative bacteria that have attained superbug status by developing resistance to the carbapenem class of antibiotics. This class of antibiotics is used as a last resort in the treatment of infections which is why CPE is so powerful. The carbapenemase enzyme produced by the bacteria disables the active molecules in the antibiotics. The powerful nature of the bacteria means that up to 50% of patients that get bloodstream infections may die. The effects of Carbapenemase-producing Enterobacteriaceae (CPE) in the body can trigger conditions such as peritonitis, pneumonia meningitis, cystitis pyelonephritis with fever, septicaemia and related infections.

Notification Of The Situation

Our service desk got a call from a hospital at 6 PM on a Wednesday to discuss the death of a patient who was brought in two days prior suffering from the advanced stages of CPE infection. With knowledge of the diagnosis, the hospital’s in-house safety team increased the hygiene level protocols to reflect the danger of the situation. CPE is transmitted through hand carriage and infected food and water.

The Situation We Met On Ground

On arrival, the hospital talked us through how they used standard procedures to ensure the situation was contained. Access to the ward was limited, and all cleaning and washing were done within the ward. However, CPE is known for its resistance to everyday cleaning agents. This meant the hospital could not guarantee the ward was safe for use by other patients. This was why they called us in. We immediately got to work to analyse the situation and devise the best possible strategy for cleaning the ward. Our method was a deep clean containment plan which was possible because the ward was already empty.

Cleaning Carbapenemase-producing Enterobacteriaceae (CPE) Through iHP Decontamination

CPE can remain on bedding, hospital equipment and even washing agents for extended periods. In fact, washing sinks can remain infection agents indefinitely if a robust decontamination process isn’t used. We used hydrogen peroxide to decontaminate every corner of the ward including bedding and then made sure the wash hand basins and sinks were properly decontaminated. Our step-by-step approach ensured we were able to avoid cross-contamination while making the environment as clean as possible.

Instant iHP Decontamination Validity Assurance

At the end of the CPE decontamination process, we used our renowned enzyme indicators to check for success. We took samples from all around the ward, including within and around the sinks to ensure that the process had worked. By 5 PM on Thursday, the particular hospital ward was open for patients once again.

Comprehensive Project Report

We provided a detailed report to the hospital at the end of our decontamination process as we always do on such projects. We commended the hospital on their handling of the situation and then provided insights on how the hospital can better handle future occurrences, especially how they can avoid spreading the bacteria towards hard to reach areas.

If the hospital hadn’t acted quickly, it could have been dealing with a large scale outbreak that could have negatively impacted the treatment of other patients and endanger their lives. CPE is rightly referred to as a superbug due to the unique challenges it presents. Hospitals and public health institutions such as care homes must, therefore, be ready to devise a strategy that will allow swift containment and decontamination.

The hospital in the case study and many others across the UK are reaping the benefits of having BioDecon as a partner. With our partnership, we provide swift and regular deep cleans in critical areas such as operating theatres and wards.

Do you want to become a partner? Contact us today on 01904 405959 BioDecon is always willing to discuss your options and provide consultations on Carbapenemase-producing Enterobacteriaceae (CPE) decontamination. Have you faced with an emergency situation already? We can swing to action right away if you contact us now.